Molecular Formula | C24H39NO7
|
Molar Mass | 453.58 |
Density | 1.36±0.1 g/cm3 (20 ºC 760 Torr) |
Melting Point | 206-207℃ |
Boling Point | 596.9±50.0 °C(Predicted) |
Specific Rotation(α) | (c, 0.21 in MeOH)+6.7;(CHCl3)+19.3;(c, 1.0 in CHCl3)+11.6 |
Solubility | Soluble in methanol, acetone, DMSO and other solvents. |
Appearance | White crystal |
pKa | 12.78±0.70(Predicted) |
Storage Condition | 2-8℃ |
MDL | MFCD22124992 |
Physical and Chemical Properties | White crystal, soluble in methanol, ethanol, DMSO and other organic solvents, derived from the processed products of Aconitum root, Ranunculaceae plant. |
In vitro study | Fuziline shows activity against pentobarbital sodiuminduced cardiomyocytes damage by obviously recovering beating rhythm and increasing the cell viability. |
In vivo study | Fuziline exhibits the mean half-life of 5.93 hours, 6.13 hours and 5.12 hours for 14 mg/kg, 2 4 mg/kg and 4 mg/kg, respectively, by oral administration in rat. |